Case Report

Sub Mitral Left Ventricular Aneurysm with Severe Mitral Regurgitation: A Case Report

Waqar A Khan1, Syed M Muhammad1, Khawaja A Muhammad2, Asad B Awan1, Syed S Ashraf1*

1Department of Cardiovascular Surgery, NICVD, Rafiqi Shaheed Road, Karachi, Sindh 75510, Pakistan

2Department of Anesthesia, NICVD, Rafiqi Shaheed Road, Karachi, 75510, Pakistan

*Corresponding author: Syed S Ashraf, Visiting Professor Cardiothoracic Surgeon. Department of Cardiovascular Surgery, NICVD, Rafiqi Shaheed Road, Karachi, 75510, Pakistan.

Received Date: 29 March 2023

Accepted Date: 03 April 2023

Published Date: 05 April 2023

Citation: Khan WA, Muhammad SM, Muhammad KA, Awan AB, Ashraf AS (2023) Sub Mitral Left Ventricular Aneurysm with Severe Mitral Regurgitation: A Case Report. Ann Case Report 8: 1252.


Sub Mitral Left Ventricular Aneurysm (SMLVA) is a very rare cardiac pathology of varied etiologies. Recently, researchers have discovered a congenital basis of this pathology rather than infection or inflammation. A majority of patients with this pathology present with shortness of breath due to severe mitral regurgitation. While echocardiography is the main method of its diagnosis, further investigations may be necessary to exclude other causes. Surgery is the mainstay of treatment for this condition to prevent its complications and to improve patient’s outcome. The case reported here is of a young woman, who presented with New York Heart Association (NYHA) class III/IV secondary to SMLVA. She was operated upon with excellent clinical results. While such cases have been reported previously in other South Asian countries, this is the first from Pakistan. 

Keywords: Sub Mitral Aneurysm; Mitral Valve Regurgitation; Left Ventricle Aneurysectomy; Mitral Valve Replacement


Sub Mitral Left Ventricular Aneurysm (SMLVA) is a rare but well recognize cardiac pathology. Multiple etiologies have been implicated [1, 4] in this clinical condition. We present a case report of patient with SMLVA with severe mitral regurgitation. Patient underwent for the repair of the left ventricular aneurysm and mitral valve replacement operation with an excellent clinical result. 

Case Report

A 23 years old south Asian female presented with 2 years history of shortness of breath. There was no history of previous heart attack, trauma and any related inflammatory or immunological systemic disease. Clinically she was in NYHA class III-IV secondary to severe mitral regurgitation. All cardiovascular related investigations including transthoracic echo (Figure 1), CT scan of the chest (Figure 2), Trans esophageal echo and coronary angiogram (normal) confirmed the diagnosis of moderate size (49×52mm) non ischemic basolateral Left ventricular aneurysm with severe mitral regurgitation.

Figure 1: Echocardiogram showing: Neck of aneurysm. Anterior mitral leaflet. SMA: Submitral LV aneurysm; LV: Left Ventricle; LA: Left Atrium.

Figure 2: CT scan: SMA with clot (Submitral Left Ventricular Aneurysm). Neck of the aneurysm. Left Ventricle (LV); Left Atrium (LA)

Operation performed on cardiopulmonary bypass. The aneurysm was present at the posteriobasal part of the left ventricle which was just larger than a golf ball (Figure 3,). Aneurysm was incised and organized thrombus was removed. (Figure 3B) Endoventricular pericardial patch sutured to normal muscle at the aneurysmal circumference using running 4-0 polypropylene suture (Figure 3C and 3D). Then aneurysmal wall was closed in two layers reinforced by Teflon felt on either side. A posterior mitral annulus was distorted, therefore, mitral valve replaced by size 29mm St Jude mechanical valve.