Annals of Case Reports

Postoperative Analgesia from Preemptive to Preventive Approach: Evolution and Clinical Implications

by Ahmed Abodonya1,2*

1Department of surgery, College of Medicine, Prince Sattam bin Abdulaziz University, Alkharj, KSA

2Department of Anesthesia, Intensive Care, and Pain Management, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

*Corresponding author: Ahmed Abodonya, Department of Anesthesia, Intensive Care, and Pain Management, Faculty of Medicine, Al-Azhar University, Cairo, Egypt

Received Date: 03 August 2025

Accepted Date: 08 August 2025

Published Date: 11 August 2025

Citation: Abodonya A (2025). Postoperative Analgesia from Preemptive to Preventive Approach: Evolution and Clinical Implications. Ann Case Report. 10: 2370. https://doi.org/10.29011/2574-7754.102370

Abstract

Pain management has shifted from a reactive approach to a proactive strategy focused on prevention. This study analyzes the development, neurophysiological foundation, and clinical uses of preemptive and preventive analgesia in the perioperative setting. Regardless of advancements in analgesic approaches, postoperative pain is frequently insufficiently managed in numerous sufferers, with more than 80% experiencing moderate to severe discomfort and up to 50% developing chronic pain after specific procedures. The shift from preemptive analgesia (interventions prior to surgical incision) to preventative analgesia (interventions during the perioperative phase) signifies our improved comprehension of pain processes. This article examines pain assessment tools, technological advancements, and evidence-based methodologies for implementing efficient perioperative pain management procedures. Multimodal strategies integrating pharmacological treatments, regional anesthesia procedures, and personalized care plans demonstrated substantial enhancements in patient outcomes, such as diminished pain severity, reduced opioid usage, and a lower occurrence of chronic postsurgical pain. Future directions highlight individualized analgesic regimens, the use of artificial intelligence, and ongoing research into innovative treatment strategies to optimize pain management and improve postoperative recovery.

Key words: Postoperative Analgesia; Preemptive Analgesia; Preventive Analgesia.

Abbreviations: IASP- international association for the study of pain; MRI- magnetic resonance imaging; ERAS- enhanced recovery after surgery; VAS- visual analogue scale; NRS- numeric rating scale; VRS- verbal rating scale; BPS- behavioral pain scale; CPOT- care pain observation tool.

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