JDDH Journal

Editorial

Intestinal tract hasthepotentialto contribute to the developmentof diseases by different mechanisms[1].Gastro Esophageal Reflux Disease (GERD) is of the most common gastrointestinal disorders,  that seen in all ages and its prevalence varies in various parts of the world. GERD is the most common predisposing factor for esophageal adenocarcinoma[2].Lifestyle and dietary habits can be effective in this disease.

L.Celaet, al. in Albania[3]reported a significant relationship between lifestyle and GERD. Also nutrition and modern diet play an important role in the incidence of this disease and it is confirmed that high intake of meat, oil, salt and calcium increases the risk of reflux esophagitis(RE) while intake of protein, vitamin C, carbohydrates, potatoes, grains, eggs and fruits reduce the risk of RE[4].

Symptoms of the disease may be similar to many other diseases, for this reason, it is causing a delay in treatment which especially in infants may be complications lead to such as esophagitis and finally Barrett’s esophagus.

There are many options such as drug therapy, endoscopy and surgery for treatment of disease but Y.chenet.al [5]noted using of Rabeprazole as a reliable and economical method in the diagnosis of GERD.

Gastroesophageal reflux is common in the pediatrics. The majority of patients indicate physiologic GER that many of these patients experience spontaneous resolutionby two years of age. The patients whocontinue to have symptoms are classified as having GERD. Treatment options include dietary orbehavioral modifications, pharmacologic intervention, andsurgical therapy. Totally, management of GERD in bothadults and children isdepend on disease severity, the degreeof symptoms and presence or absence of complications ofGER[6].

L Corvaglia by investigation pathology, diagnosis, and treatment of GERD in children used thestepwise method with non-pharmacologic interventions and limited drugs [7].

However, there are many studies about diagnosis, treatment and causes of Gastroesophageal Reflux Disease, and the aim of this paper is an overview of the last important research in the field of GERD due to its high prevalence.

• Shahverdi E. (2016) Probiotics and Gastrointestinal Diseases. International Journal of Digestive Diseases.
• Lagergren J1, Bergström R, Lindgren A, Nyrén O (1999) Symptomatic gastroesophageal reflux as a risk factor for esophageal adenocarcinoma. See comment in PubMed Commons below N Engl J Med 340: 825-831.
• Çela L, Kraja B, Hoti K, Toçi E, Muja H et al (2013). Lifestyle characteristics and gastroesophageal reflux disease: a population-based study in Albania. Gastroenterology research and practice.2013.
• Wu P1, Zhao XH, Ai ZS, Sun HH, Chen Y, et al. (2013) Dietary intake and risk for reflux esophagitis: a case-control study. See comment in PubMed Commons below Gastroenterol Res Pract 2013: 691026.
• Chen Y, Wang F, Jiang Y, Wang C, Yao L et al (2013). The diagnostic significance of coapplying a rabeprazole test with the SF-36 for gastro esophageal reflux disease. Gastroenterology research and practice. 2013.
• Jackson HT and Kane TD (2013). Surgical management of pediatric gastroesophageal reflux disease. Gastroenterology research and practice. 2013.
• Corvaglia L, Monari C, Martini S, Aceti A, Faldella G et al (2013). Pharmacological therapy of gastroesophageal reflux in preterm infants. Gastroenterology research and practice. 2013.