Abstract

Haemorrhagic Cystitis (HC) is a complex condition to manage with a highly variable clinical presentation. Non-operative management strategies, including intravesical treatments, serve to reduce risks and complications associated with surgery. Intravesical alum instillation is a commonly used therapy, particularly for patients that are not responsive to conservative management and ineligible for surgical intervention. Available data suggests a positive response rate to intravesical alum instillation. Common side effects included bladder spasm and pain, however, no serious or life-threatening events were reported. The long-term durability is uncertain. Patient summary: In this report we looked at the outcomes from intravesical bladder irrigation with alum. We found alum was reported as a efficacious and safe therapy, with minimal side effects. We conclude that alum instillation can be considered as a method to cease haemorrhagic cystitis, particularly in patients who are unable or unwilling to be considered for more invasive treatment methods, such as cystectomy.

Keywords: Alum Instillation; Haemorrhagic Cystitis; Intra-Vesical Therapy; Rapid Review