Archives of Gastroenterology and Hepatology

Does Non-Sedative Colonoscopy Possible? Evaluation of Painful Sensation, Cecal Intubation and Adenoma Detection Rate

by Cheng-Ju Lee1, Ming-Yao Su1-4*

1Department of Internal Medicine, New Taipei Municipal TuCheng Hospital, Taiwan

2Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital Linkou Branch, Taiwan

3Chang Gung University College of Medicine, Taiwan

4Taiwan Association for the Study of Small Intestinal Diseases, Taiwan

*Corresponding author: Ming-Yao Su, Department of Internal Medicine, New Taipei Municipal TuCheng Hospital, Taiwan

Received Date: 17 December, 2025

Accepted Date: 29 December, 2025

Published Date: 31 December, 2025

Citation: Lee CJ, Su MY (2025) Does Non-Sedative Colonoscopy Possible? Evaluation of Painful Sensation, Cecal Intubation and Adenoma Detection Rate. Arch Gastroenterol Hepatol 5: 114. https://doi.org/10.29011/AGEH-114.000114

Abstract

Background: Colon is a long and tortuous tube, so colonoscopy is more invasive and painful procedure then esophagogastroduodenoscopy. Aim: To identify factors that predict painful colonoscopy, cecal intubation rate (CIR) and adenoma detection rate (ADR) in non-sedative colonoscopy. Methods: From January to Aug 2015, A total of 1260 consecutive patients underwent non-sedative colonoscopy were enrolled. This was a prospective, observational study. Prospective data’s collection including patients’ characteristics, previous medical and surgical history, and indications for colonoscopy, bowel preparation status, insertion time and length of colonoscopy. Patients’ anxiety levels were recorded before the procedure and painful sensation were recorded after the procedure by Likert scale from one study nurse blinded to the procedure. Endoscopists’ experiences were recorded also. These factors were analyzed for the correlations of painful sensation, Cecal Intubation Rate (CIR) and Adenoma Detection Rate (ADR). Results: There were no significant differences for the painful sensation of colonoscopy and the factors mentioned above by univariate analysis except gender and patient’s anxiety level. While, patient’s anxiety level, endoscopist’s experience were correlate with painful sensation of colonoscopy by multivariate analysis. Male and older than 50 years patients had higher ADR. While operator’s experience increased both CIR and ADR. Conclusions: In our study, high anxiety level of patients, female gender and unexperienced endoscopists may correlate with painful feeling under non-sedative colonoscopy, while experienced endoscopists and male gender had higher ADR.

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