Journal of Digestive Diseases and Hepatology

Assessing the Status of Post-Endoscopic Retrograde Cholangiopancreatography Cholecystectomy in Patients with Gallstone Disease

by Vanessa I. Rodriguez1*, Afrin Naz2, Rasika Patil2, Athanasios Tsalatsanis2, Brijesh B. Patel3,4

1Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, TN, USA

2Department of Internal Medicine, University of South Florida, Tampa, FL, USA

3Division of Digestive Diseases and Nutrition, University of South Florida, Tampa, FL, USA

4James A. Haley VA Hospital, Tampa, FL, USA

Corresponding author: Vanessa I. Rodriguez, Department of Internal Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, Tampa General Cir, Tampa, Florida, USA

Received Date: 23 July 2025

Accepted Date: 04 August 2025

Published Date: 07August 2025

Citation: Rodriguez VI, Naz A, Patil R, Tsalatsanis A, Patel BB (2025) Assessing the Status of Post-Endoscopic Retrograde Cholangiopancreatography Cholecystectomy in Patients with Gallstone Disease. J Dig Dis Hepatol 10: 228. https://doi.org/10.29011/2574-3511.100228

Abstract

Introduction: Gallstone pancreatitis, choledocholithiasis, cholelithiasis, and cholangitis are common reasons for hospitalization in the US. However, despite efforts to standardize guidelines, the timing of cholecystectomy following endoscopic retrograde cholangiopancreatography (ERCP) remains variable across clinical practice. This study was performed to highlight discrepancies between clinical practice and standardized guidelines and protocols. Methods: Data was obtained from the TriNetX federated health research network. Included were patients diagnosed with cholangitis, gallstone pancreatitis, choledocholithiasis, or cholelithiasis who underwent ERCP between January 2022 and November 2023, with focused placed on rate of cholecystectomy at the index event in each diagnostic group. Results : Out of 1,043 patients diagnosed with gallstone pancreatitis, 10 underwent cholecystectomy following ERCP, representing a rate of 0.1%. Among 1,658 patients diagnosed with choledocholithiasis, 12 underwent cholecystectomy post-ERCP, equating to a rate of 0.72%. For the 528 patients diagnosed with cholangitis, 10 underwent cholecystectomy post-ERCP, accounting for a rate of 1.90%. Conclusion: Our data supports the notion that many institutions have yet to implement standard of care practices for cholecystectomy into their management of gallstone disease. 

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