Gurbanova J.F, Nabiyeva K.Z and Salimova A.T
Laboratory of Medical Genetics of Scientific and Research Institute of Obstetrics and Gynecology, Azerbaija
Background: Prenatal diagnosis are aspects of prenatal care that focus on detecting problems with the pregnancy as early as possible. Screening can detect problems such as neural tube defects, chromosome abnormalities, and gene mutations that would lead to genetic disorders and birth defects. First trimester screening tests can begin as early as 10 weeks. These usually involve a blood tests and an ultrasound. Second trimester screening tests occur between 14 and 18 weeks. They can involve a blood test, which tests whether a mother is at risk for having a child with chromosomal abnormalities or neural tube defects, as well as an ultrasound. A special ultrasound called a nuchal translucency ultrasound is performed between the 11th and 14th weeks of pregnancy. When there’s more fluid than normal, this means there’s a higher risk of chromosomal abnormalities.
Materials and methods: 1562 pregnant women were examined at dual (PAPP-A, ? hCG) and triple (AFP, hCG and free E 3) marker tests. Analysis is performed on an enzyme immunoassay; serum is used for analysis.
Results: 873 pregnant women were examined for dual test at the Scientific and Research Institute of Obstetrics and Gynecology in 2017, 88 patients (10%) were at the risk group. 689 patients were examined for triple test, 50 patients (7,3%) were at the risk group.
Conclusion: Complete survey pregnant on the chromosomal abnormalities allows to advance diagnose pathology 60% of cases.
Gurbanova J.F. was born in 1972 in Baku. She graduated from Azerbaijan Medical University in 1995. After postgraduated studies in Obstetrics and Gynecology Department of Azerbaijan Medical University, Obstetrics and Gynecology Department of Moscow Medical Academy she got PhD and MD degrees. In 2004-2013 years she worked as co-director of Scientific Research Institute of Obstetrics and Gynecology, and from 2013 till present time, she is the director of the same institute. At the same time, she is the president of Azerbaijan Association “Supporting the development of gynecology and perinatology”.