"Assessment of prevalence of asymptomatic bacteriuria and antibiotic susceptibility and its risk factors in pregnant women living in Sabzevar City from 2014 to 2015"

Mitra Eftekhariyazdi, Behnaz Souizi and Manije Yousefi Moghadam

University of Medical Sciences, Iran

DOI: 10.29011/2577-2236-C1-006

Introduction: symptomatic bacteriuria is a common problem during pregnancy. Delayed diagnosis and treatment may end up in harmful events for both mother and fetus. Physiological changes of urinary system during pregnancy facilitate the growth of microorganisms and cause this infection. This study was performed with aim to evaluate the prevalence of asymptomatic bacteriuria and determine the antibiotic susceptibility and its risk factors in pregnant women.

Methods: This cross-sectional study was performed on 220 pregnant women referred to Shahidan Mobini Hospital in Sabzevar in 2014-2015. Sterile urine sample of pregnant women was analyzed in terms of full urine test and culture. Antibiogram of isolated bacteria was done with colony count greater than 100000 by Bauer-Kirby Disk Diffusion. Individual characteristics of the subjects were recorded in the checklist.

Results: In this study which was performed on 220 pregnant women, 7% of pregnant women had asymptomatic bacteriuria. Significant relationship was found between asymptomatic bacteriuria and education level (p<0.001), socioeconomic status (p=0.002), regional living area (p=0.004), history of previous urinary tract infection (p<0.001), and history of renal complications (p=0.028). However, no significant relationship was observed between asymptomatic bacteriuria and mode of last delivery, number of pregnancies and systemic underlying diseases (P>0.05). Most common isolated organisms were Escherichia coli and staphylococcus ureus. Antibiogram results showed that cotrimoxasol, nitroforantoin, ciproflouxasin and nalidixic acide are appropriate antibiotics for treatment of patients.

Conclusion: Asymptomatic bacteriuria has favorable prevalence in Sabzevar city. In the screening of this situation, considering individual and social characteristics seems to be necessary.

Mitra Eftekhariyazdi is a Perinatologist and Assistant professor in Department of Obstetrics & Gynecology of Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran. She did her postdoctoral research at Tehran University. She has published more than 9 research articles, and edited two books in Perinatology field. She is Deputy Head of Education.


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