Urinary Tract Infection (UTI) is a common pathology both in the community and in the hospital. In recent years, there has been an increase in the incidence
of antibiotic resistance of UI-causing organisms, particularly due to the emergence of enterobacteria with Extended-Spectrum Beta-Lactamase (ESBL).
Goal: The aim of this work was to study the epidemiology of germs responsible for urinary tract infections, as well as their sensitivity to
antibiotics at the University Hassan II Center of Fez in all patients presenting for ECBU during a period from March 2018 to May 2018.
Materials and Methods: This is a prospective study conducted at the level of the microbiology laboratory, over a period of two months in all
patients presenting to this structure for ECBU during this period. The culture was made according to the usual techniques, and the antibiogram was performed
according to the recommendations of the Committee of the antibiogram of the French Society of Microbiology (CA-SFM).
Results: Out of 520 urine samples, 63 met the criteria for urinary tract infection (12, 12%). The sex ratio F / H is 2.5. The epidemiology of
urinary tract infections in our laboratory is broadly comparable to literature data for age, sex, field, and the most frequently responsible organism
Escherichia coli 76.2 %. However, differences in resistance are observed: higher resistance to betalactamines, quinolone regeneration,
fluoroquinolones and cotrimoxazole. The UI was common in patients with the concept of abuse of antibiotics (64.9%), hospital (58.73%), diseases of the
urinary tract (50.79%), the survey (30, 16%) and diabetes (34.92%). The prevalence of ESBL-producing enterobacterial urinary tract infections in our study
was 16.6 % among all urinary enterobacterial infections. The strains of E. coli and in Klebsiella pneumoniae isolated ESBL expressed
respectively in 12.5 and 28.5% of cases.
Conclusion: The distribution of strains in our study is comparable to the literature, however, antibiotic resistance is higher in our series,
a result probably of inappropriate use of these molecules in our country, hence the need to foresee a good strategy of supply and dispensing of these
molecules as well as the revision of the empirical treatment of IU in our country.
UTI: Urinary Tract Infection; ESBL: Extended-Spectrum Beta-Lactamase; CA-SFM: The Committee of the Antibiogram of the French Society of Microbiology