1Department of Oral Medicine, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, China
2Department of Hematology, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, China
3Department of Pathology, Shanxi Provincial People’s Hospital, Taiyuan, Shanxi, China
4Department of Otology and Skull Base Surgery of ENT, Eye and ENT Hospital, Fudan University, Shanghai, China
5ENT Institute, Eye and ENT Hospital of Fudan University, Shanghai, China
Corresponding Author*: Ning Cong, Department of Otology and Skull Base Surgery of ENT, Eye and ENT Hospital, Fudan University, ENT Institute, Eye and ENT Hospital of Fudan University, 83 Fenyang Road, Xuhui Distinct, Shanghai, China
Received Date: 24 August, 2021
Accepted Date: 03 September, 2021
Published Date: 07 September, 2021
Background: A palatal ulcer is a non-specific clinical presentation and might be the first sign of a potentially fatal disease; thus, accurate diagnosis is challenging.
Case Summary: Here, we present two cases with palatal mucosal ulcers both located on the left side and with similar clinical appearance. Case 1 was diagnosed with pulmonary Tuberculosis (TB) and case 2 was diagnosed with Extranodal NK/T-Cell Lymphoma, nasal type (ENKTCL). Both cases responded well to systemic therapy, and the palatal ulcers completely healed without recurrence.
Conclusion: TB and ENKTCL should be included in the differential diagnosis of palatal ulcer of unknown etiology.
Keywords: Diagnosis; Extranodal NK/T Cell Lymphoma; Palatal Ulcer; Pulmonary Tuberculosis
AbbreviationsCT: Computed Tomography; CRP: C-Reactive Protein; DNA: Deoxyribonucleic Acid; EBV: Epstein-Barr Virus; ENKTCL: Extranodal NK/T Cell Lymphoma, Nasal Type; EBER: EpsteinBarr Virus Encoded RNA; ESR: Erythrocyte Sedimentation Rate; Hb: Hemoglobin; HIV: Human Immunodeficiency Virus; HE: Hematoxylin and Eosin; HE: Hematoxylin and Eosin; ISH: In Situ Hybridization; LDH: Lactate Dehydrogenase; MRI: Magnetic Resonance Imaging; NEUT#: Neutrophil Count; PET/CT: Positron Emission Tomography/Computed Tomography; RNA: Ribonucleic Acid; TB: Tuberculosis; WBC: White Blood Cell