Annals of Case Reports (ISSN: 2574-7754)

Case Report

The Role of Fetal MRI and US in the Prenatal Diagnosis of Mixed Adrenal Neuroblastoma: A Case Report and Brief Literature Review

George V Hadjidekov1*, Asenova D2, Gornev R3

*Corresponding Author: George V Hadjidekov, Department of Radiology, University Hospital “Lozenets, Sofia 1407, Bulgaria.

Received Date: 12 September, 2021

Accepted Date: 22 September, 2021

Published Date: 25 September, 2021


Neuroblastoma is a malignant tumor which develops from the neural crest cells of the sympathetic nervous system. Neuroblastoma represents 8-10% of all childhood neoplasms making it the most common extracranial solid tumor in childhood. It is sometimes occasionally detected prenatally during second and third trimester screening. Cross-sectional imaging is needed not only for assessment of the origin, extent of the tumor, local invasion, vascularity and calcifications, but also for staging of neuroblastoma, presence of lymphadenopathy and metastatic spread. Prenatal ultrasound (US) is first-line modality in evaluating neuroblastomas followed by fetal magnetic resonance imaging (MRI) for precise determination the extend of the tumor within the abdominal cavity or the retroperitoneal space. This report aims to present the role of fetal MRI as a valuable adjunct to US in a case of prenatally detected neuroblastoma, which is an important issue for prognostic counseling. Furthermore, beside this case study we would like to contribute a brief review of the literature.

Keywords: Neuroblastoma; antenatal ultrasound; fetal MRI

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