Role of Sugammadex, Significance of its Dose and Timing for Rocuronium Induced Medically Refractory Anaphylactic Shock: A Case Report

Abstract

Rocuronium-induced anaphylaxis (RIA) during the perioperative period is a rare life-threatening event. Despite, the available evidence of sugammadex for RIA, there has been no standardized approach for the management of this critical scenario. Therefore, we propose a systematic approach for diagnosing and treating RIA. We, also present a case report of a medically refractory anaphylactic shock from rocuronium, which was effectively treated with sugammadex. Our literature review and experience suggest that sugammadex can be an effective treatment option for medically refractory rocuroniuminduced anaphylaxis, and thus should be part of the armamentarium for RIA.

Keywords: Sugammadex, Rocuronium, Life-threatening anaphylaxis, Perioperative anaphylaxis, Rocuronium-induced anaphylaxis, Sugammadex dosing and timing.